It’s arguably the tie of the round and the Wizards will fancy their chances against the Principality Premiership’s basement outfit. The game will be played the weekend of March 23.
The All Whites are three-times winners of this cup – Aberavon were finalists in 1974 and 1975 but have yet to lift the trophy.
In the last round Swansea beat Newport 17-14 at Rodney Parade thanks to a last minute penalty goal from Cameron Clement. Aberavon touched down five times in beating Beddau 44-6.
Other quarter-final ties are: Blackwood v Carmarthen Quins, Ebbw Vale v Pontypridd and Neath v Bargoed.
In the Swalec Bowl, meanwhile, Glyncorrwg will face Swansea side Penlan if they can first overcome Blaenavon. Penlan put paid to the students of Cardiff Medicals 21-7 in the last round.